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PRO EDI: improving how equity, diversity and inclusion is handled in evidence synthesis

Equity, diversity and inclusion in evidence synthesis

Few single randomised trials change practice, and this is how it should be.  Instead, bodies of evidence from several trials are collated through evidence synthesis, generally systematic reviews.  It is the results of these reviews that lead to practice and guideline changes.  Because evidence synthesis can have important consequences for which care is provided, and how, it is essential that equity, diversity and inclusion is explicitly considered within synthesis.

PRO EDI is an initiative led by Trial Forge, Evidence Synthesis Ireland and the Campbell Collaboration to try and make it easier for those doing systematic reviews, especially ones including randomised trials, to explicitly consider equity, diversity and inclusion in their reviews.  The initiative benefits from an international advisory group to help us make PRO EDI relevant to all reviews and reviews, wherever the reviewers may be based in the world, and whatever the topic of the review. Our starting points were PROGRESS-PLUS, which maps out equity, diversity and inclusion topics that reviewers should consider; and the INCLUDE Ethnicity Framework, which has operationalised consideration of ethnicity for trial design.

How you can help

PRO EDI has developed a table for extracting information about participant characteristics from randomised trials included in a systematic review.  Having these data is the starting point of being able to make judgements about whether the review findings apply equally to all those who could benefit from the treatment or initiative being reviewed.

We would be delighted if you used PRO EDI in your review.  We would also be extremely grateful for examples you could send us (e.g., a link to a review) of PRO EDI being used.  We would be interested in your general feedback too, especially on the time taken to use PRO EDI (e.g., does PRO EDI use up a lot of time, or more or less what you would have used before? Does it use less time?).  

Note that currently, PRO EDI is only specifically designed for randomised controlled trials; however, we think it can be useful for other study designs too.

  • The PRO EDI participant characteristics table can be downloaded free here.
  • We’ve designed a feedback form for you to use and are looking for one completed form per review, which can be downloaded here.

There is some brief guidance in the PRO EDI table itself, but we are working on some more detailed guidance to go with it.  We expect this to be ready in April 2024.

Any comments or questions about PRO EDI, please email info@trialforge.org

How to cite

PRO EDI participant characteristics table 22/3/2024; pro-edi-improving-how-equity-diversity-and-inclusion-is-handled-in-evidence-synthesis [insert access date].

Licencing and permission to use

Once we have completed development work, the plan is to make the PRO EDI materials available for free here. You will not need a licence or to ask us for permission to use the PRO EDI table or associated documents. We only ask that you acknowledge the tool, if you have used it, by citing it (see citation on this page).

Funder

The PRO EDI development work has been publicly funded by Ireland’s Health Research Board through Evidence Synthesis Ireland, grant ESI-2021-001.

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