Participants are contacted to let them know that the trial team will be sending a questionnaire to them soon.
Prenotification cards may increase retention slightly.
An increase of 3% (95% confidence interval = -3% to 10%).
GRADE Low certainty.
We recommend that trialists consider using pre-notification cards.
See Resource bundle below for details on how to use prenotification cards.
Imagine initial retention is 65% of those approached. You have a trial with 100 participants that needs responses from 80 to meet its statistical power calculations. Retention of 65% means that you will be 15 responses short (see chart below).
Now imagine using prenotification cards. The chart below shows the impact of an absolute increase of 3% (95% CI = -3% to 10%). Retention is now 68%, which means our best estimate is that you would now be only 12 responses short.
Trial Forge will make trials more efficient by looking for marginal gains across all trial processes, from research question to implementation into routine care. It will encourage everyone connected with trials to be more sceptical of what we do by asking for the evidence behind all of our trial decisions.