Trial Diversities

Learning from completed INCLUDE Ethnicity Frameworks The INCLUDE Ethnicity Framework aims to help trial teams think specifically about which ethnic groups should be included in their trial for its results to be widely applicable, and what challenges there may be to making this possible. One of the potential challenges of using the INCLUDE Frameworks is […]

Why we undertook the PRESS project Clinical trials are important, but recruiting and retaining participants is challenging. Fewer than half of trials meet their recruitment goals, leading to wasted time, money, and effort for research teams and participants. Additionally, poor retention, when participants drop out before the study ends, comprises trial outcomes. Recruitment and retention

Download the report Download our report by clicking here Our eight recommendations to strengthen partnerships between researchers and diverse ethnic communities are shown in brief in the picture below. The full text of our recommendations is available here.  The Evidence to Decision Framework we used to collate our findings, and support the recommendations is available here.

Equity, diversity and inclusion in evidence synthesis Few single randomised trials change practice, and this is how it should be.  Instead, bodies of evidence from several trials are collated through evidence synthesis, generally systematic reviews.  It is the results of these reviews that lead to practice and guideline changes.  Because evidence synthesis can have important

Also see the NIHR INCLUDE Impaired Capacity to Consent Framework. Ethical medical research relies on the principle of informed consent. However, obtaining valid consent can be difficult in certain situations. For instance, some individuals may find themselves unable to provide consent due to sudden impairing medical conditions like strokes or conditions that cause a gradual