Trial Diversities

Beyond sex-specific organs, there are numerous disease and treatment-related differences between sexes. Unfortunately, historically, research has heavily relied on male participants, leading to the common practice of extrapolating results and assuming applicability to female patients. This approach can be misleading and potentially harmful with female patients experiencing higher rates of adverse drug reactions and having […]

The INCLUDED (INCLUsivity through improving the practice anD utility of Ethnicity Data collection in trials) project aimed to find out how data on ethnicity are being collected and handled in clinical trials, what those from diverse ethnic groups think about this, whether this has any bearing on their participation in research, and how the data

SCOPE These recommendations have been designed to aid researchers designing clinical trials to consider barriers to including older patients in their trial. The recommendations can also help researchers to develop strategies to attempt to address such barriers in order to improve the design and conduct of health and social care research. Although the recommendations were

The STRIDE project involved discussion in late 2022/early 2023 with ten panels of public contributors, trialists, health professionals and others.  These panels discussed a total of 23 trials with the aim of saying which ethnic groups the trials needed to include and what proportion of the trial population they should be. We have published a

SCOPE This framework has been designed to aid researchers, who are designing clinical trials, to consider barriers to including patients from socioeconomically disadvantaged backgrounds in their trial. The framework can also help researchers to develop strategies to attempt to address such barriers in order to improve the design and conduct of clinical research. Although this