Trial Diversities

Also see the NIHR INCLUDE Impaired Capacity to Consent Framework. Ethical medical research relies on the principle of informed consent. However, obtaining valid consent can be difficult in certain situations. For instance, some individuals may find themselves unable to provide consent due to sudden impairing medical conditions like strokes or conditions that cause a gradual […]

Also see the NIHR INCLUDE Socioeconomic Disadvantage Framework.  Socioeconomic status is a measure of an individual’s social standing, determined by a combination of factors such as education, income, and occupation. People who are socioeconomically disadvantaged experience less favourable social and economic conditions compared to the majority in their society. This disadvantage is multifaceted and can

Beyond sex-specific organs, there are numerous disease and treatment-related differences between sexes. Unfortunately, historically, research has heavily relied on male participants, leading to the common practice of extrapolating results and assuming applicability to female patients. This approach can be misleading and potentially harmful with female patients experiencing higher rates of adverse drug reactions and having

The INCLUDED (INCLUsivity through improving the practice anD utility of Ethnicity Data collection in trials) project aimed to find out how data on ethnicity are being collected and handled in clinical trials, what those from diverse ethnic groups think about this, whether this has any bearing on their participation in research, and how the data

SCOPE These recommendations have been designed to aid researchers designing clinical trials to consider barriers to including older patients in their trial. The recommendations can also help researchers to develop strategies to attempt to address such barriers in order to improve the design and conduct of health and social care research. Although the recommendations were